New concepts and design methodologies in Materials Science will be discussed and disseminated in this session. Additional topics include the creation of new devices, the synthesis of materials systems and integration of materials into architectures for various operational environments. These require a profound understanding of the physical, chemical, and biological interactions among the intermolecular forces and interfacial components. In order to systematically design complex materials systems, multiple layers of abstractions and various mathematical models to represent component behavior in different layers will also be exploited. Presentations in this session include the development of new tools for sensing, assembling, processing, manipulating, manufacturing and integration along scales, controlling and testing the structures, devices, design and architecture of concepts, software specialized for metals, ceramics, and composite materials. One can envision materials systems that sense and gather information and analyze and react to that information, and architectures, and novel separation systems with intermolecular and interfacial resolution.